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Human & Experimental Toxicology
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Self-Poisoning with the β-Blocker Bisoprolol

A. Tracqui

Institut de Médecine Légale, Faculté de Médecine de Strasbourg, 11, rue Humann, 67000 Strasbourg, France

P. Kintz

Institut de Médecine Légale, Faculté de Médecine de Strasbourg, 11, rue Humann, 67000 Strasbourg, France

P. Mangin

Institut de Médecine Légale, Faculté de Médecine de Strasbourg, 11, rue Humann, 67000 Strasbourg, France

B. Lenoir

Service d'Anesthésie-Réanimation, Centre Hospitalier des Armées Lyautey, 1, rue des Canonniers, 67000 Strasbourg, France

A case of bisoprolol self-poisoning resulting in full recovery of the patient is described. The peak plasma level of bisoprolol was 541 ng ml-1. Sinus bradycardia was the only symptom observed, suggesting that cardioselectivity and absence of membrane stabilizing activity contribute to reduce the severity of β-blocker intoxication.

Human & Experimental Toxicology, Vol. 9, No. 4, 255-256 (1990)
DOI: 10.1177/096032719000900409
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