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Human & Experimental Toxicology
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Two Cases of Organophosphate Poisoning with Development of Intermediate Syndrome

M. Karademir

Department of Internal Medicine, Çukurova University Medical School, Adana, Turkey

F. Ertürk

Department of Internal Medicine, Çukurova University Medical School, Adana, Turkey

R. Koçak

Department of Internal Medicine, Çukurova University Medical School, Adana, Turkey

Two cases of intermediate syndrome caused by organophosphorus poisoning are reported. Trichlorfon, propoxur (a carbamate pesticide) and fenthion were ingested in both attempts at suicide. After successful conventional therapy during the cholinergic phase, but before the time when the onset of delayed neuropathy might be expected, an intermediate syndrome developed. It affected the proximal limb muscles, neck flexors and respiratory muscles 2 d after pesticide ingestion. The two patients needed respiratory support. Recovery from the intermediate syndrome was complete in both patients, although one subsequently developed delayed neuropathy.

Human & Experimental Toxicology, Vol. 9, No. 3, 187-189 (1990)
DOI: 10.1177/096032719000900312
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