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Human & Experimental Toxicology
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Inhibition of β-glucuronidase in Human Urine by Ascorbic Acid

J.C. Young

Environmental Health Sciences Program, School of Public Health, University of Massachusetts, Amherst, MA 01003, USA

E.M. Kenyon

Environmental Health Sciences Program, School of Public Health, University of Massachusetts, Amherst, MA 01003, USA

E.J. Calabrese

Environmental Health Sciences Program, School of Public Health, University of Massachusetts, Amherst, MA 01003, USA

The effects of oral supplementation of ascorbic acid (1500 mg d-1) on urinary β-glucuronidase (β-G) activity was assessed in a double-blind crossover study design over a 3-week period. The subjects on ascorbic acid treatment displayed a statistically significant (P < 0.05) decrease in β-G with an approximate decrease of 25%.

Human & Experimental Toxicology, Vol. 9, No. 3, 165-170 (1990)
DOI: 10.1177/096032719000900308


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