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Toxicological Data after Heroin Overdose

Institut de Médecine Légale, 11, rue Humann, 67000 Strasbourg, France

P. Mangin

Institut de Médecine Légale, 11, rue Humann, 67000 Strasbourg, France

A.A. Lugnier

Institut de Médecine Légale, 11, rue Humann, 67000 Strasbourg, France

A.J. Chaumont

Institut de Médecine Légale, 11, rue Humann, 67000 Strasbourg, France

Capillary gas chromatography with selective nitrogen detection was employed to quantify morphine and 6-monoacetylmorphine in biological fluids and tissues in five deaths attributed to heroin injection overdose. The minimum lethal concentration found was 0.021 µg morphine per ml of blood. In all cases, 6-monoacetylmorphine was identified in urine, confirming heroin abuse.

Human & Experimental Toxicology, Vol. 8, No. 6, 487-489 (1989)
DOI: 10.1177/096032718900800609


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