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Human & Experimental Toxicology
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Fatal Phenolphthalein Poisoning with Fulminant Hepatic Failure and Disseminated Intravascular Coagulation

P.S. Sidhu

Department of Gastroenterology; UMDS Guy's Campus

M.L. Wilkinson

Department of Gastroenterology; UMDS Guy's Campus

G.E. Sladen

Department of Gastroenterology; UMDS Guy's Campus

M.I. Filipe

Department of Histopathology, UMDS Guy's Campus

P.A. Toseland

Department of Chemical Pathology, UMDS Guy's Campus

A 32-year-old female ingested an unknown quantity of Nylax tablets containing phenolphthalein. This results in widespread organ involvement, predominantly causing liver damage and disseminated intravascular coagulation. The eventual cause of death was massive liver necrosis. We suggest that phenolphthalein was responsible for the widespread damage.

Human & Experimental Toxicology, Vol. 8, No. 5, 381-384 (1989)
DOI: 10.1177/096032718900800509
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