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Hyperaluminaemia Associated with Oral Citrate and Aluminium Hydroxide

Department of Medicine, Division of Nephrology, Medical College of Virginia, MCV Station, Box 160, Richmond, VA 23298, USA

A.C. Schoolwerth

Department of Medicine, Division of Nephrology, Medical College of Virginia, MCV Station, Box 160, Richmond, VA 23298, USA

1 A hospitalized patient with renal failure receiving oral aluminium hydroxide was found to have a blood aluminium level of 3124 µg/l (116 µmol/l) .

2 The extremely high aluminium concentration was attributed to the concurrent use of an oral citrate solution which converted the aluminium to a more soluble and absorbable form.

3 The combination of oral aluminium and citrate should be avoided in patients with poor renal function.

Human & Experimental Toxicology, Vol. 8, No. 1, 45-47 (1989)
DOI: 10.1177/096032718900800108


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