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Clinical and Sub-clinical Lead Poisoning: A Laboratory Perspective

Regional Laboratory for Toxicology, Dudley Road Hospital, Birmingham B 18 7QH, UK

S.S. Brown

Regional Laboratory for Toxicology, Dudley Road Hospital, Birmingham B 18 7QH, UK

1 The background, scope and limitations of laboratory methods for the diagnosis of inorganic dead poisoning are outlined in the context of the work of a specialist clinical laboratory for trace element analysis.

2 Data for blood lead, haemoglobin and erythrocyte zinc protoporphyrin concentrations are presented in cases of clinical and sub-clinical poisoning due to accidental or occupational exposure.

3 Data from population surveys of children and adults subject to either environmental or occupational exposure are also shown.

4 In general, analysis for lead in an appropriate specimen of blood offers the single most useful index of exposure.

5 The importance of good accuracy control in such measurements is emphasized.

Human & Experimental Toxicology, Vol. 7, No. 5, 503-513 (1988)
DOI: 10.1177/096032718800700518


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