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Human & Experimental Toxicology
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The Toxic Effects of Alpha-Chloralose

H.M. Thomas

Regional Poisoning Treatment Centre and University Department of Clinical Chemistry, The Royal Infirmary, Edinburgh EH3 9YW, UK

D. Simpson

Regional Poisoning Treatment Centre and University Department of Clinical Chemistry, The Royal Infirmary, Edinburgh EH3 9YW, UK

L.F. Prescott

Regional Poisoning Treatment Centre and University Department of Clinical Chemistry, The Royal Infirmary, Edinburgh EH3 9YW, UK

1 Alpha-chloralose, formed by the condensation of glucose with chloral, is used as a rodenticide and in the control of bird pests.

2 In two cases of poisoning with alpha-chloralose the clinical features included coma and generalized convulsions resembling the effects of strychnine more than those of chloral hydrate.

3 The principles of management are the support of vital functions in the unconscious patient and removal of unabsorbed poison by gastric lavage. Diazepam may be used to control convulsions.

Human & Experimental Toxicology, Vol. 7, No. 3, 285-287 (1988)
DOI: 10.1177/096032718800700311
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