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Human & Experimental Toxicology
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Severe Ethylene Glycol Butyl Ether Poisoning. Kinetics and Metabolic Pattern

M.O. Rambourg-Schepens

Centre Anti-Poisons, S.A.M.U., Hospital de la Maison Blanche. 51092 Reims cedex, France

M. Buffet

Centre Anti-Poisons, S.A.M.U., Hospital de la Maison Blanche. 51092 Reims cedex, France

R. Bertault

Centre Anti-Poisons, S.A.M.U., Hospital de la Maison Blanche. 51092 Reims cedex, France

M. Jaussaud

Centre Anti-Poisons, S.A.M.U., Hospital de la Maison Blanche. 51092 Reims cedex, France

B. Journe

Centre Anti-Poisons, S.A.M.U., Hospital de la Maison Blanche. 51092 Reims cedex, France

R. Fay

Laboratoire de Pharmacologie-Toxicologie, Hopital de la Maison Blanche, 51092 Reims Cedex, France

D. Lamiable

Laboratoire de Pharmacologie-Toxicologie, Hopital de la Maison Blanche, 51092 Reims Cedex, France

A case of severe poisoning with ethylene glycol butyl ether (EGBE) after massive ingestion is described.

Deep coma, metabolic acidosis, hypokalaemia, haemoglobinuria, oxaluria and a transitory rise in the serum creatinine level were observed.

The elimination of the various metabolites butoxyacetic acid and oxalate was assessed in urine and a metabolic pattern for EGBE is suggested.

Human & Experimental Toxicology, Vol. 7, No. 2, 187-189 (1988)
DOI: 10.1177/096032718800700215


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