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Human & Experimental Toxicology
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A Ceramic Glazer Presenting with Extremely High Lead Levels

D.S. Ooi

Division of Biochemistry, Ottawa Civic Hospital, 1053 Carling Avenue, Ottawa, K1Y 4E9, Department of Biochemistry, University of Ottawa, Ontario, Canada

S.L. Perkins

Division of Biochemistry, Ottawa Civic Hospital, 1053 Carling Avenue, Ottawa, K1Y 4E9, Department of Biochemistry, University of Ottawa, Ontario, Canada

A case of lead poisoning in a ceramic glazer is reported. The patient had an extremely high level of blood lead at 29.5 µmol/l, and many of the laboratory features of lead toxicity: normocytic anaemia with marked basophilic stippling, abnormal blood and urinary porphyrins, and elevated liver enzymes. Surprisingly, the patient had no electromyographic evidence of neurologic involvement. The patient was treated with intravenous EDTA-calcium followed by oral penicillamine. Urinary porphyrin and porphyrin precursor excretion followed an interesting pattern, correlating with the chelator used. This patient illustrates that extremely high blood lead level can be achieved through the oral route in an adult.

Human & Experimental Toxicology, Vol. 7, No. 2, 171-174 (1988)
DOI: 10.1177/096032718800700211


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