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Human & Experimental Toxicology
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A Report of Overdose with Astemizole

J.C. Kingswood

Departments of Medicine and Pharmacology and Therapeutics, University of Wales College of Medicine, Llandough Hospital, Penarth, South Glamorgan CF6 1XX, Wales, UK

P.A. Routledge

Departments of Medicine and Pharmacology and Therapeutics, University of Wales College of Medicine, Llandough Hospital, Penarth, South Glamorgan CF6 1XX, Wales, UK

J.H. Lazarus

Departments of Medicine and Pharmacology and Therapeutics, University of Wales College of Medicine, Llandough Hospital, Penarth, South Glamorgan CF6 1XX, Wales, UK

A case is reported of a 14-year-old girl who took an overdose of 200 mg of astemizole. There were no serious adverse clinical or laboratory sequelae, with only mild sedation and no anticholinergic adverse effects. The apparent half-life of this dose over the next 37 h was 31 h.

Human & Experimental Toxicology, Vol. 5, No. 1, 43-44 (1986)
DOI: 10.1177/096032718600500108


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