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Methylene Dianilene: a New Toxic Cause of Visual Failure with Hepatitis

Department of Medicine, Falkirk and District Royal Infirmary, Majors Loan, Falkirk, Stirlingshire FK1 5QE

P.D. McSorley

Tennent Institute of Ophthalmology, Western Infirmary, Glasgow G11 6NT, Scotland, UK

I.G. Syme

Department of Medicine, Falkirk and District Royal Infirmary, Majors Loan, Falkirk, Stirlingshire FK1 5QE

A 28-year-old man ingested methylene dianilene in potassium carbonate and y-butyrolactone. He developed toxic optic neuritis, with severe visual dysfunction (not previously reported in humans), prolonged toxic hepatitis, with disturbed liver-function tests 18 months after the incident, and other more transient effects. The course of his illness is described and the literature on methylene dianilene toxicity is reviewed.

Human & Experimental Toxicology, Vol. 4, No. 1, 61-66 (1985)
DOI: 10.1177/096032718500400107


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