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Human & Experimental Toxicology
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Management of Quinine Overdose

G.F. Browne

Respiratory Intensive Care Unit, Royal Victoria Hospital, Belfast BT12 6BA, Northern Ireland

D.L. Coppel

Respiratory Intensive Care Unit, Royal Victoria Hospital, Belfast BT12 6BA, Northern Ireland

The successful management of a case of quinine overdose with blindness is described. From a review of the literature, treatment of moderate poisoning with ingestion of < 10 g of quinine should consist of immediate and thorough gastric lavage, forced acid diuresis, immediate bilateral stellate ganglion blockage repeated if there is clinical improvement in vision. With a larger overdose or when coma or convulsions occur haemodialysis, peritoneal dialysis or preferably haemoperfusion should be considered.

Human & Experimental Toxicology, Vol. 3, No. 5, 399-402 (1984)
DOI: 10.1177/096032718400300505
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