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Efficacy: UK Experience

Centre for Rheumatic Diseases, University Department of Medicine, Royal Infirmary, Glasgow, Scotland, UK

1 The UK experience of Distalgesic efficacy is examined, and 18 trials have been reviewed, of which only five were controlled and only three contained a placebo.

2 Three trials are examined in detail and the problems of trial methodology discussed.

3 The assessment of analgesic effect in chronic painful conditions presents considerable problems. Despite the fact that Distalgesic appears to be a useful analgesic in the clinical situation, long-term controlled studies of its effectiveness in chronic pain are still awaited.

Human & Experimental Toxicology, Vol. 3, No. 1 suppl, 221s-227S (1984)
DOI: 10.1177/096032718400300119


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