This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Khan, A Articles by Mahmood, F Search for Related Content PubMed PubMed Citation Articles by Khan, A Articles by Mahmood, F Pubmed/NCBI databases Compound via MeSH Substance via MeSH Hazardous Substances DB FORMALDEHYDE Social Bookmarking                         What's this?

Pathological effects of formalin (37% formaldehyde) feeding in female Japanese quails (Coturnix coturnix japonica)

Department of Veterinary Pathology, University of Agriculture, Faisalabad-38040, Pakistan; ahrar{at}fsd.paknet.com.pk

H A Bachaya

M Z Khan

F Mahmood

Department of Veterinary Pathology, University of Agriculture, Faisalabad, Pakistan

The aim of this study was to determine the pathological effects of formalin on female quails. Seventy-five 1-day-old female Japanese quails (Coturnix coturnix japonina) were divided into five equal groups (A–the eighth week. No clinical signs were observed in quails fed 2.5 mL formalin/kg feed. Depression, dullness and anorexia were prominent in quails fed 20 mL formalin/kg feed. Feed intake, body weight, egg production and egg weight together with absolute and relative weight of organs, erythrocyte and leukocyte counts, hemoglobin concentration and hematocrit were decreased at higher doses, i.e., 10 and 20 mL formalin/kg feed. Total serum proteins and globulin significantly increased (P B / 0.05) in all formalin fed quails compared to control birds. No gross lesions were observed in the 2.5 mL formalin/kg fed group. At higher doses (10 and 20 mL formalin/kg feed) hemorrhages on the thigh muscles, decreased weight and reduction in area and folds of different segments of oviduct were recorded. Reduced size of liver, heart and kidneys was recorded in quails fed 20 mL formalin/kg feed compared to controls and other birds. The histopathological changes in oviduct consisted of degeneration of mucosal glands characterized by vacuolation of nuclei of cells. It was concluded from the study that formalin feeding to female quails at 2.5 mL/kg feed is without harmful effects, however, higher doses are not without health risks.

Key Words: biochemistry • egg production • feed intake • female Japanese quails • formalin • hematology • organ weight • pathological effects

Human & Experimental Toxicology, Vol. 24, No. 8, 415-422 (2005)
DOI: 10.1191/0960327105ht543oa


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				A. Khan, S. M. Hussain, and M. Z. Khan Effects of formalin feeding or administering into the crops of white leghorn cockerels on hematological and biochemical parameters. Poult. Sci., September 1, 2006; 85(9): 1513 - 1519. [Abstract] [Full Text] [PDF]