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Human & Experimental Toxicology
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Organochlorine and organophosphorus pesticide residues in breast milk from Bhopal, Madhya Pradesh, India

Rashmi Sanghi

Facility of Ecological and Analytical Testing, 302 Southern Laboratories, Indian Institute of Technology, Kanpur-208016, India, rsanghi{at}iitk.ac.in

M KK Pillai

Department of Zoology, University of Delhi, New Delhi-110 007, India

T R Jayalekshmi

The Other Media, B-14, Gulmohar Park, New Delhi-110 045, India

A Nair

Toxics Link, H-14, Jangpura Extension, New Delhi-110 014, India

HCH isomers, endosulfan, malathion, chlorpyrifos, and methyl-parathion were monitored in human milk samples from Bhopal, Madhya Pradesh. The endosulfan concentrations were highest and exceeded the S-HCH, chlorpyrifos, and malathion concentrations by 3.5-, 1.5-, and 8.4-fold, respectively. Through breast milk, infants consumed 8.6 times more endosulfan and 4.1 times more malathion than the average daily intake levels recommended by the World Health Organization. A correlation analysis (r values) between mothers' age and the content of the chemicals accumulated in breast milk indicated a substantial degree of correlation for malathion (r–0.5). The other chemicals showed low to negligible correlation with donor age.

Key Words: ADI • bioconcentration • correlation coefficients • human milk • organochlorine and organophosphorous pesticides

Human & Experimental Toxicology, Vol. 22, No. 2, 73-76 (2003)
DOI: 10.1191/0960327103ht321oa
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