SAGE Journals Online
Advertisement
Sign In to gain access to subscriptions and/or personal tools.

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Advertisement

Sign In to gain access to subscriptions and/or personal tools.
Human & Experimental Toxicology
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Jayjock, M A
Right arrow Articles by Lewis, P G
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Jayjock, M A
Right arrow Articles by Lewis, P G
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Jayjock and Lewis reply

M A Jayjock

Rohm and Haas Company, Spring House, Pennsylvania 19477, USA

P G Lewis

Rohm and Haas Company, Bristol, Pennsylvania 19007, USA; Rohm and Haas Company, PO Box 0904, Spring House, Pennsylvania 19477, USA; rstmaj{at}rohmhaas.com

The current state-of-the-science, in our opinion, is incapable of accurately predicting the human health risk at environmental exposures to chemicals. We believe that dose-response models represent an integral part of the scientific method but that all models require valid scientific data in the realm of actual exposure in order to be derived and function properly. Given this current state, the evidence to date and the promise of hormesis to provide a detectable signal at low-dose, we view it as a variable and valuable hypothesis worthy of significant scientific effort.

Key Words: exposure limit • hormesis • low-dose • modelling • risk assessment

Human & Experimental Toxicology, Vol. 21, No. 7, 407-408 (2002)
DOI: 10.1191/0960327102ht271xx
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?




Advertisement