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Review of Implications of hormesis for industrial hygieneDivision of Environmental and Occupational Health, School of Public Health, PO Box 807 Mayo, 420 Delaware Street SE, University of Minnesota, Minnesota, USA; brosseau{at}umn.edu Hormesis is an appealing concept when considered from the evolutionary viewpoint. It may provide a new approach to deriving the `no observed adverse effect level for occupational exposures to chemicals. An over-reliance on mathematical modeling without a clear understanding of exposures and health outcomes stymies current scientific decision-making. Care must be taken, however, as not all endpoints will exhibit a hormetic response.
Key Words: hormesis industrial hygiene no observed adverse effect level occupational exposure limit threshold toxicology
Human & Experimental Toxicology, Vol. 21, No. 7,
395 (2002) |
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