This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Filali, A Articles by Creppy, E E Search for Related Content PubMed PubMed Citation Articles by Filali, A Articles by Creppy, E E Social Bookmarking                         What's this?

Ochratoxin A in human plasma in Morocco: a preliminary survey

Laboratoire de Toxicologie d'Urgence et de Suivi Thérapeutique du Centre Anti Poison du Maroc, Rabat, Morocco

A M Betbeder

Laboratoire de Toxicologie et Hygiène Appliquée, Université Victor Segalen, Bordeaux 2, 146 rue Léo-Saignat, Bordeaux Cedex 33076, France. anne-marie.betbeder{at}tox.u-bordeaux2.fr

I Baudrimont

Laboratoire de Toxicologie et Hygiène Appliquée, Université Victor Segalen, Bordeaux 2, Bordeaux Cedex 33076, France

A Benayada

Laboratoire du Génie des Procédés, Ecole Mohammadia d’Ingénieurs, Rabat, Morocco

R Soulaymani

Laboratoire de Toxicologie d’Urgence et de Suivi Thérapeutique du Centre Anti Poison du Maroc, Rabat, Morocco

E E Creppy

Laboratoire de Toxicologie et Hygieène Appliquée, Université Victor Segalen, Bordeaux 2, Bordeaux Cedex 33076, France

Available epidemiological information seems to indicate that Balkan endemic nephropathy is associated with consumption patterns involving foodstuffs contaminated with ochratoxin A (OTA) and with a higher frequency of OTA-positive blood samples. The aim of this preliminary study was to assess OTA concentrations in human plasma in Morocco. Therefore, samples from 309 healthy volunteers (213 males, 96 females) were analysed. The analyses revealed that 60% of the human plasma sampled was positive for OTA (61.5% in the male and 56% in the female population), and an average concentration of 0.29 ng// /mL (0.31 ng///mL in males, 0.26 ng// /mL in females). The highest concentration found was 6.59 ng// /mL. The results suggest that the Moroccan population is exposed to OTA, even though the OTA plasma levels are lower than that reported in some North African countries.

Key Words: human plasma • Morocco • ochratoxin A • prevalence

Human & Experimental Toxicology, Vol. 21, No. 5, 241-245 (2002)
DOI: 10.1191/0960327102ht249oa


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				H. Assaf, A.-M. Betbeder, E. E Creppy, M. Pallardy, and H. Azouri Ochratoxin A levels in human plasma and foods in Lebanon Human and Experimental Toxicology, October 1, 2004; 23(10): 495 - 501. [Abstract] [PDF]

				R Froquet, G Le Drean, and D Parent-Massin Effect of Ochratoxin a on human haematopoietic progenitors proliferation and differentiation: an in vitro study Human and Experimental Toxicology, July 1, 2003; 22(7): 393 - 400. [Abstract] [PDF]