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Human & Experimental Toxicology
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Experiments, analyses and decisions: hormesis in ecotoxicology

A J Bailer

Center for Environmental Toxicology and Statistics, Department of Mathematics and Statistics, Miami University, Oxford, Ohio 45056, USA

We have been challenged by Peter Chapman to consider the implication of hormesis for both ecotoxicology and ecological risk assessment. A consideration of his proposal led to the following observations and comments. I echo his comments related to the need for experimental designs and statistical tools that accommodate and address hormesis. I expand on his comments related to the basic question of how adverse responses should be defined for hormetic concentration–response patterns for both individual species and populations. Finally, I reflect on the notion of the implication of incorrectly detecting or not detecting hormesis in an ecosystem.

Key Words: optimal designs • risk characterization

Human & Experimental Toxicology, Vol. 20, No. 10, 507-509 (2001)
DOI: 10.1191/096032701718120346
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