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Myoglobinuric Renal Failure due to Drug-induced Rhabdomyolysis

Institut für Nephrologie, Kontumazgarten 14-18, 8500 Nuremburg

H. Horstkotte

Department of Internal Medicine, Medizinische Hochschule, Hannover

K.W. Rumpf

Department of Internal Medicine, Universität Göttingen, F.R.G.

1 Two cases of drug-induced rhabdomyolysis, one of them presenting with acute myoglobinuric renal failure are described.

2 The pathogenesis of rhabdomyolysis and renal failure in our cases is discussed with reference to work published by other authors.

3 Whereas there seems to be obvious evidence for direct toxic drug-muscle interaction, the mechanism for the development of myoglobinuric renal failure remains unclear.

Human & Experimental Toxicology, Vol. 2, No. 2, 197-203 (1983)
DOI: 10.1177/096032718300200204


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