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Transplacental Carcinogenesis with Radioactive Phosphorus

Department of Morbid Anatomy, The London Hospital, London, E1 1BB

J. Amerigo

Department of Morbid Anatomy, The London Hospital, London, E1 1BB, Depto de Anatomia Patologica, Hospital Universitario, Sevilla, Spain

C. Nickols

Department of Morbid Anatomy, The London Hospital, London, E1 1BB

K.V. Swettenham

Department of Morbid Anatomy, The London Hospital, London, E1 1BB

1 An attempt was made to produce a model of osteogenic sarcoma using ³²P transplacentally.

2 Fetal tissues appeared to be resistant to irradiation as no tumour was induced at an increased frequency in treated animals.

3 Tumours that normally occur in our strain (Sprague-Dawley rats) showed a clear tendancy to occur earlier in post-natal life in treated animals compared with controls.

Human & Experimental Toxicology, Vol. 2, No. 1, 49-62 (1983)
DOI: 10.1177/096032718300200104


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