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Human & Experimental Toxicology
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Phenytoin poisoning after using Chinese proprietary medicines

K K Lau

Department of Medicine and Geriatrics, Princess Margaret Hospital, Kwai Chung, Hong Kong SAR, China

C K Lai

A YW Chan

Department of Pathology, Princess Margaret Hospital, Kwai Chung, Hong Kong SAR, China

We report a case of poisoning resulting from the use of Chinese proprietary medicines (CPM) containing antic-onvulsants phenytoin, carbamazepine and valproate. The manufacturer's information leaflets did not mention any of these prescription drugs. As a consequence, the patient was admitted comatose due to severe phenytoin poisoning. We are not aware of any reported case of severe poisoning due to CPM adulterated with anticonvulsants and this is possibly the first case.

Human & Experimental Toxicology, Vol. 19, No. 7, 385-386 (2000)
DOI: 10.1191/096032700678816115
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