This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Chang, C-Y Articles by Lin, T-J Search for Related Content PubMed PubMed Citation Articles by Chang, C-Y Articles by Lin, T-J Pubmed/NCBI databases Compound via MeSH Substance via MeSH Medline Plus Health Information Esophagus Disorders Hazardous Substances DB GLYCINE GLYPHOSATE Social Bookmarking                   What's this?

Clinical impact of upper gastrointestinal tract injuries in glyphosate-surfactant oral intoxication

Y-C Peng

D-Z Hung

W-H Hui

D-Y Yang

Department of EmergencyMedicine, Taichung Veterans GeneralHospital, Taichung, Taiwan 40705, Republic of China

T-J Lin

Department of EmergencyMedicine, Taichung Veterans GeneralHospital, Taichung, Taiwan 40705, Republic of China; National Yang-Ming University, Taipei, Taiwan 112, Republic of China

1. 1 Fifty patients with glyphosate-surfactant oral ingestion were studied with upper gastrointestinal (UGI) endoscopic grading using Zargar's modified grading system for mucosal corrosive injury.
   
2. 2 Esophageal injury was seen in 68% of the patients, gastric injury in 72%, and duodenal injury in 16%. There were no grade 3 injuries. The upper gastrointestinal tract injuries caused by glyphosate-surfactant were minor in comparison with those by other strong acids.
   
3. 3 The WBC count, amount of glyphosate-surfactant ingested, length of hospital stay and the occurrence of serious complications increased markedly in the group which had grade 2 esophageal injuries. Thus, the severity of the esophageal injuries may be a prognostic factor for the patient with glyphosate-surfactant ingestion.
   
4. 4 The UGI endoscopy may be indicated for grading esophageal injury in patients who have ingested glyphosate-surfactant in amounts greater than 100 ml. Physicians should pay more attention to the patients with grade 2 or 3 esophageal injuries to prevent serious complications and to provide aggressive supportive care.
   

Key Words: glyphosate-surfactant • esophageal injury • endoscopy • corrosive injury

Human & Experimental Toxicology, Vol. 18, No. 8, 475-478 (1999)
DOI: 10.1191/096032799678847078


CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?