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Human & Experimental Toxicology
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Hemodynamic abnormalities in sodium monofluoroacetate intoxication

Chih-Hsien Chi

Department of Emergency Medicine, National Cheng-Kung University Medical College and Hospital, 138 Sheng-Li Road, Tainan City, Taiwan

Tin-Kwang Lin

Department of Internal Medicine, Sin-Lau Matou Christian Hospital, Tainan County, Taiwan

Kuan-Wen Chen

Department of Emergency Medicine, National Cheng-Kung University Medical College and Hospital, 138 Sheng-Li Road, Tainan City, Taiwan

Hypotension is one of the most important predictors of mortality in sodium monofluoroacetate (SMFA) intoxication. This paper reports the hemodynamic response in one fatal and another survival case of SMFA intoxication. Despite correction of hypovolemia and with inotropic support, the patients remained in shock. Hemodynamic observations have provided evidence that shock after SMFA intoxication is due to diminished systemic vascular resistance and increased cardiac output. This is the first report in which such an invasive hemodynamic investigation has been recorded in a clinical case of SMFA intoxication.

Key Words: poisoning • sodium monofluoroacetate • Swan-Ganz catheterization

Human & Experimental Toxicology, Vol. 18, No. 6, 351-353 (1999)
DOI: 10.1191/096032799678840200
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[Abstract] [PDF]


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