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Human & Experimental Toxicology
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*ATROPINE
*MAGNESIUM COMPOUNDS
*MAGNESIUM SULFATE
*PARATHION
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Q-T interval prolongation and pleomorphic ventricular tachyarrhythmia (`Torsade de pointes') in organophosphate poisoning: report of a case

Ming-Hsi Wang

Department of Internal Medicine, National Taiwan University Hospital, Taipei

Chuen-Den Tseng

Department of Internal Medicine, National Taiwan University Hospital, Taipei

Shyi-Yann Bair

Department of Internal Medicine, Cheng-Ching General Hospital, Taichung, Taiwan, ROC

1 A 63-year-old woman presented with drowsy consciousness and dyspnea, followed by respiratory failure, after taking a bottle of parathion for suicide.

2 Sinus tachycardia was noted initially by ECG and Q-T interval prolongation with pleomorphic ventricular tachyarrhythmia (`Torsade de pointes') occurred on the third day of admission.

3 Torsade de pointes was relieved by magnesium sulfate and atropine sulfate intravenously. Q-T interval returned to normal on the fifth day of admission.

4 Practicing physicians should be aware of this uncommon type of cardiac toxicity caused by organophosphate poisoning, Q-T interval prolongation and pleomorphic ventricular tachyarrhythmia.

Key Words: Q-T prolongation • Torsade de pointes • organo-phosphate poisoning

Human & Experimental Toxicology, Vol. 17, No. 10, 587-590 (1998)
DOI: 10.1177/096032719801701010
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