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Human & Experimental Toxicology
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What's this?

An unusual poisoning with the unusual pesticide amitraz

Philippe G Jorens

Department of Intensive Care Medicine, University Hospital of Antwerp, Wilrijkstraat 10, B-2650 Edegem, Belgium

Eric Zandijk

Department of Intensive Care Medicine, University Hospital of Antwerp, Wilrijkstraat 10, B-2650 Edegem, Belgium

Luc Belmans

Department of Intensive Care Medicine, University Hospital of Antwerp, Wilrijkstraat 10, B-2650 Edegem, Belgium

Paul JC Schepens

Toxicology Centre, University of Antwerp, UIA, Universiteitsplein 1, B-2610 Wilrijk Straat, Belgium

Leo L Bossaert

Department of Intensive Care Medicine, University Hospital of Antwerp, Wilrijkstraat 10, B-2650 Edegem, Belgium

Amitraz, 1,5 di-(2,4-dimethylphenyl)-3-methyl-1,3,5-tria za-penta-1,4-diene, a formamidine pesticide, is used worldwide. It causes side-effects in animals that resemble those caused by pure {alpha}2-adrenergic agonist drugs such as clonidine. Data on poisonings in humans are scanty. We report on a case of human poisoning with amitraz with typical signs of {alpha}2-adrenoreceptor stimulation.

Key Words: adrenergic • adrenergic agonists • amitraz • bradycardia • formamidine • intoxication

Human & Experimental Toxicology, Vol. 16, No. 10, 600-601 (1997)
DOI: 10.1177/096032719701601008


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