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Human & Experimental Toxicology
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Increased sister chromatid exchange (SCE) frequencies in lymphocytes from traffic policemen exposed to automobile exhaust pollution

R. Chandrasekaran

Department of Environmental Sciences, Bharathiar University, Coimbatore 641 046

Plp Samy

Department of Environmental Sciences, Bharathiar University, Coimbatore 641 046

Pbk Murthy

Carcinogenicity Division, Fredrick Institute of Plant Protection and Toxicology, Padappai 601 301, India

Sister chromatid exchange (SCE) frequencies were deter mined in peripheral lymphocytes from traffic policemen drawn from various busy traffic points of Madras metro in India. These policemen were under constant exposure to automobile exhaust pollution during their 8 h work schedule. Analysis of SCE frequencies revealed a sig nificantly greater number of SCE/cell in these policemen as against the matched control population. Sixty percent of these subjects who remained in the service after 5 years showed insignificant but higher values of SCE than in the initial analysis.

Key Words: sister chromatid exchange • vehicle exhaust • occupa tional exposure • traffic policemen

Human & Experimental Toxicology, Vol. 15, No. 4, 301-304 (1996)
DOI: 10.1177/096032719601500405


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