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Human & Experimental Toxicology
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Neurotoxicity following the ingestion of a Chinese medicinal plant, Alocasia macrorrhiza

Tyk Chan

Department of Clinical Pharmacology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong

LY Chan

Department of Medicine, Prince of Wales Hospital, Shatin, New Territories, Hong Kong

LS Tam

Department of Medicine, Prince of Wales Hospital, Shatin, New Territories, Hong Kong

Jajh Critchley

Department of Clinical Pharmacology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong

1 A case of poisoning due to the raw root tuber of a Chinese medicinal plant, Alocasia macrorrhiza is pre sented.

2 The patient developed neurological (severe pain and numbness in the perioral area and throat) and gastro intestinal (nausea, vomiting, abdominal pain) symptoms immediately after eating the root tuber.

3 A. macrorrhiza has properties and morphology very similar to another medical plant, A. odora. The root tuber of the latter is known to contain a neurotoxin, sapotoxin.

Key Words: Alocasia macrorrhiza • herbal medicines • neuro toxicity • sapotoxin

Human & Experimental Toxicology, Vol. 14, No. 9, 727-728 (1995)
DOI: 10.1177/096032719501400905


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