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Metal accumulation in human kidney cortex: mutual interrelations and effect of human factorsNational Institute of Toxicology, Department of Seville, PO Box 863, 41080 Seville, Faculty of Pharmacy, University of Seville, PO Box 874, 41012 Seville, Faculty of Chemistry of Seville, PO Box 553, 41012 Seville, Spain
National Institute of Toxicology, Department of Seville, PO Box 863, 41080 Seville, Faculty of Pharmacy, University of Seville, PO Box 874, 41012 Seville, Faculty of Chemistry of Seville, PO Box 553, 41012 Seville, Spain
National Institute of Toxicology, Department of Seville, PO Box 863, 41080 Seville, Faculty of Pharmacy, University of Seville, PO Box 874, 41012 Seville, Faculty of Chemistry of Seville, PO Box 553, 41012 Seville, Spain
National Institute of Toxicology, Department of Seville, PO Box 863, 41080 Seville, Faculty of Pharmacy, University of Seville, PO Box 874, 41012 Seville, Faculty of Chemistry of Seville, PO Box 553, 41012 Seville, Spain 1 Different metals were analysed in 77 post mortem samples of human renal cortex. 2 The concentrations of the metallic ions conformed to known distribution frequencies. In abnormal cases calcu lations were based on non parametric techniques. 3 There was no appreciable difference between the val ues found for each element and those described by other authors in other populations. 4 Statistically established correlations indicated that Zn was the element which was most strongly related to the others. 5 The influence of individual factors on metal concentra tions was considered. Significant differences occurred only in Pb between sexes, and in Cd with age. There was no sign that drug abuse influenced the accumulation of metals in renal cortex.
Key Words: human kidney cortex • metals • distribution • interrelations • human factors
Human & Experimental Toxicology, Vol. 14, No. 4,
335-340 (1995) |
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