SAGE Journals Online
Advertisement
Sign In to gain access to subscriptions and/or personal tools.

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Advertisement

Sign In to gain access to subscriptions and/or personal tools.
Human & Experimental Toxicology
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Naylor, G.
Right arrow Articles by Harrison, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Naylor, G.
Right arrow Articles by Harrison, J.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Gastrointestinal iron and cobalt absorption and iron status in young rats and guinea pigs

Gpl Naylor

National Radiological Protection Board, Chilton, Didcot, Oxon OX11 ORQ, UK

JD Harrison

National Radiological Protection Board, Chilton, Didcot, Oxon OX11 ORQ, UK

The gastrointestinal absorption of Fe and Co by rats and guinea pigs of different ages was measured by comparing the whole-body retention of 59Fe and 57Co after oral and intraperitoneal administrations. The age-groups studied included newborn, weanlings and adults. The absorption of both Fe and Co decreased markedly with age in both rats and guinea pigs. In the rat, absorption remained ele vated during the suckling period, while in the guinea pig absorption decreased markedly during suckling. In both species, Fe and Co absorption were similar, and remained elevated above adult values for some time after weaning. The generally greater absorption of Fe and Co by rats than by guinea pigs and the longer duration of maximal absorp tion in the rats may have involved differences in Fe status in the two species and differences in the timing of gut mat uration.

Key Words: gastrointestinal absorption • iron • cobalt • iron status

Human & Experimental Toxicology, Vol. 14, No. 12, 949-954 (1995)
DOI: 10.1177/096032719501401203
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 Drug Metab. Dispos.Home page
S. S. Anand, K.-B. Kim, S. Padilla, S. Muralidhara, H. J. Kim, J. W. Fisher, and J. V. Bruckner
ONTOGENY OF HEPATIC AND PLASMA METABOLISM OF DELTAMETHRIN IN VITRO: ROLE IN AGE-DEPENDENT ACUTE NEUROTOXICITY
Drug Metab. Dispos., March 1, 2006; 34(3): 389 - 397.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. Rev.Home page
J. Pacha
Development of Intestinal Transport Function in Mammals
Physiol Rev, October 1, 2000; 80(4): 1633 - 1667.
[Abstract] [Full Text] [PDF]


Advertisement