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Human & Experimental Toxicology
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*Substance via MeSH
Hazardous Substances DB
*MALATHION
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Unusual Manifestations after Malathion Poisoning

A. Dive

Centre de toxicologie clinique, U.C.L. Saint-Luc, Bruxelles

P. Mahieu

Centre de toxicologie clinique, U.C.L. Saint-Luc, Bruxelles

R. Van Binst

Centre de toxicologie clinique, U.C.L. Saint-Luc, Bruxelles

A. Hassoun

Centre de toxicologie clinique, U.C.L. Saint-Luc, Bruxelles

D. Lison

Centre de toxicologie clinique, U.C.L. Saint-Luc, Bruxelles

H. De Bisschop

Centre de toxicologie clinique, U.C.L. Saint-Luc, Bruxelles

B. Nemery

Longtoxicologie, K. U. Leuven, Leuven, Belgium

R. Lauwerys

Centre de toxicologie clinique, U.C.L. Saint-Luc, Bruxelles

We report a case of organophosphate poisoning with a commercial preparation of malathion (deliberate ingestion of Malathane Garden Spray: malathion 15% in isopropyl alcohol) in which the initial cholinergic crisis was followed by cardiac, pulmonary, neurological and renal manifestations. They occurred when erythrocyte and plasma cholinesterases were reactivating. A chemical analysis of the pesticide preparation revealed, apart from malathion itself, the presence of isopropylmalathion and O,O,S-trimethylphosphorothioate.

Although pure malathion is regarded as one of the safest organophosphate insecticides, this observation underlines the possibility of severe complications after exposure to a preparation which has been stored for a long period of time.

Human & Experimental Toxicology, Vol. 13, No. 4, 271-274 (1994)
DOI: 10.1177/096032719401300409
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