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Human & Experimental Toxicology
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Fulminant Hepatitis following Exposure to Dichlorohydrin — Report of Two Cases

Tadahiko Shiozaki

Department of Traumatology, Osaka University Medical School, Osaka, Japan

Yasumitsu Mizobata

Department of Traumatology, Osaka University Medical School, Osaka, Japan

Hisashi Sugimoto

Department of Traumatology, Osaka University Medical School, Osaka, Japan

Toshiharu Yoshioka

Department of Traumatology, Osaka University Medical School, Osaka, Japan

Tsuyoshi Sugimoto

Department of Traumatology, Osaka University Medical School, Osaka, Japan

A 34-year-old man suffered from fulminant hepatitis after cleaning a tank in which there were traces of dichlorohydrin. In spite of daily plasma exchanges, he died 10 days after exposure. A 27-year-old man with much lighter exposure showed only slight liver dysfunction. This is the first report of lethal injury following exposure to dichlorohydrin.

Human & Experimental Toxicology, Vol. 13, No. 4, 267-270 (1994)
DOI: 10.1177/096032719401300408
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