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An Acute Mercuric Mercury Poisoning: Chemical Speciation of Hair Mercury Shows a Peak of Inorganic Mercury Value

Department of Human Ecology, Faculty of Medicine, University of Tokyo, Hongo 7-3-1, Bunkyoku, Tokyo, 113 Japan

T. Hongo

Department of Human Ecology, Faculty of Medicine, University of Tokyo, Hongo 7-3-1, Bunkyoku, Tokyo, 113 Japan

N. Matsuo

Department of Human Ecology, Faculty of Medicine, University of Tokyo, Hongo 7-3-1, Bunkyoku, Tokyo, 113 Japan

H. Imai

Department of Human Ecology, Faculty of Medicine, University of Tokyo, Hongo 7-3-1, Bunkyoku, Tokyo, 113 Japan

M. Nakazawa

Department of Human Ecology, Faculty of Medicine, University of Tokyo, Hongo 7-3-1, Bunkyoku, Tokyo, 113 Japan

T. Abe

Department of Human Ecology, Faculty of Medicine, University of Tokyo, Hongo 7-3-1, Bunkyoku, Tokyo, 113 Japan

Y. Yamamura

Department of Public Health, St. Marianna University School of Medicine, 2095, Sugao, Miyamae-ku, Kawasaki, 213 Japan

M. Yoshida

Department of Public Health, St. Marianna University School of Medicine, 2095, Sugao, Miyamae-ku, Kawasaki, 213 Japan

H. Aoyama

Department of Public Health, St. Marianna University School of Medicine, 2095, Sugao, Miyamae-ku, Kawasaki, 213 Japan

A woman ingested a dose of sublimate (approximately 0.9 g) in an attempted suicide. She survived and recovered in response to a combination of therapies including chelate (BAL) therapy, plasma exchange, haemodialysis and peritoneal dialysis.

Serum inorganic mercury concentration, urinary inorganic mercury excretion and hair inorganic and organic mercury and selenium concentrations, along the length from the scalp to the distal part, were measured. Longitudinal analysis of hair, revealed a peak in inorganic mercury corresponding to the time of mercury ingestion. Organic mercury and selenium in the hair had different patterns of longitudinal variation from that of inorganic mercury. The biological half-life (23.5 d) of serum inorganic mercury levels was in good agreement with values previously reported in the literature.

Human & Experimental Toxicology, Vol. 11, No. 1, 53-57 (1992)
DOI: 10.1177/096032719201100109


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