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Human & Experimental Toxicology
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Drug-related Acute Medical Admissions

Lawrence E. Ramsay

University Department of Therapeutics, Royal Hallamshire Hospital, Glossop Road, Sheffield

Stephen Freestone

University Department of Therapeutics, Royal Hallamshire Hospital, Glossop Road, Sheffield

Joseph H. Silas

University Department of Therapeutics, Royal Hallamshire Hospital, Glossop Road, Sheffield

1 A survey of urgent admissions to a general medical unit in Sheffield in 1978 showed that about 25% of admissions were caused by drug-related illness; 18% by self-poisoning, 3.1% by definite or probable adverse reactions, 3.1 % by possible adverse reactions, and 1.4 % by non-compliance with drug treatment. These patients accounted for 10.8% of the bed use by patients admitted urgently.

2 Drug-related admissions to the unit did not increase between 1974 and 1980.

3 The use of barbiturates for self-poisoning declined sharply, while that of paracetamol increased steadily. Self-poisoning with dextropropoxyphene appeared to peak in 1978, and then decline.

4 While drug-related illness caused the admission of 81 % of all patients under the age of 30 years, they rarely came to harm. Self-poisoning had a high mortality in older patients, and they were also the principal sufferers from adverse drug reactions.

Human & Experimental Toxicology, Vol. 1, No. 4, 379-386 (1982)
DOI: 10.1177/096032718200100403
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