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Human & Experimental Toxicology
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Severe Renal Failure in Hydralazine-Induced Lupus

A.J. Sinclair

Department of Clinical Pharmacology, St. Bartholomew's Hospital, London EC 1A 7BE

S.J. Warrington

Department of Clinical Pharmacology, St. Bartholomew's Hospital, London EC 1A 7BE

1 An elderly hypertensive woman developed severe renal failure owin hydralazine-induced lupus, although the dose never exceeded 150 mg da

2 Renal biopsy appearances were consistent with an immune-comp mediated glomerulonephritis.

3 Withdrawal of the drug was followed by rapid recovery in spite structural damage to the kidney.

Human & Experimental Toxicology, Vol. 1, No. 1, 65-69 (1981)
DOI: 10.1177/096032718100100107


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